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Serena Rinaldo Selected Research

Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)

1/2021Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments.
11/2020Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity.
1/2018The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
1/2016A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

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Serena Rinaldo Research Topics

Disease

11Neoplasms (Cancer)
01/2022 - 03/2015
4Lung Neoplasms (Lung Cancer)
01/2021 - 01/2016
3Infections
04/2022 - 10/2019
2Neoplasm Metastasis (Metastasis)
06/2021 - 11/2020
2Adenocarcinoma of Lung
01/2021 - 11/2020
2Prostatic Neoplasms (Prostate Cancer)
10/2019 - 01/2017
2Ischemia
01/2019 - 08/2009
2Persistent Infection
08/2014 - 11/2012
2Dehydration (Water Stress)
11/2007 - 05/2007
1Insulin Resistance
04/2021
1Alzheimer Disease (Alzheimer's Disease)
04/2021
1Mitochondrial Diseases (Mitochondrial Disease)
04/2021
1Cognitive Dysfunction
04/2021
1Starvation
11/2020
1Hypoxia (Hypoxemia)
10/2019
1Brain Ischemia (Cerebral Ischemia)
01/2019
1Bacterial Infections (Bacterial Infection)
08/2013
1Crohn Disease (Crohn's Disease)
08/2013
1Inflammation (Inflammations)
08/2012

Drug/Important Bio-Agent (IBA)

5Serine (L-Serine)FDA Link
01/2021 - 03/2015
4Amino AcidsFDA Link
06/2021 - 11/2020
4Proteins (Proteins, Gene)FDA Link
04/2021 - 05/2007
4CarbonIBA
01/2021 - 01/2016
4Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA
01/2021 - 01/2016
4NitritesIBA
08/2012 - 05/2007
3Glucose (Dextrose)FDA LinkGeneric
04/2021 - 01/2017
3Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2021 - 01/2016
3Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2014 - 08/2009
2RNA (Ribonucleic Acid)IBA
01/2021 - 01/2019
2Phosphotransferases (Kinase)IBA
11/2020 - 05/2017
2Biological ProductsIBA
11/2019 - 01/2017
2Protein Isoforms (Isoforms)IBA
01/2018 - 01/2016
2EnzymesIBA
01/2016 - 11/2007
1Anti-Bacterial Agents (Antibiotics)IBA
04/2022
1Neurotransmitter Agents (Neurotransmitter)IBA
06/2021
1Insulin (Novolin)FDA Link
04/2021
1HexosaminesIBA
04/2021
1Messenger RNA (mRNA)IBA
01/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2020
1Adenosine Monophosphate (AMP)IBA
11/2020
1Adenylate KinaseIBA
11/2020
1Adenosine Triphosphate (ATP)IBA
11/2020
1Adenosine (Adenocard)FDA LinkGeneric
10/2019
1Toll-Like Receptor 3IBA
10/2019
1Chemokine CX3CL1IBA
01/2019
1Neuroprotective AgentsIBA
01/2019
1Thymidine Monophosphate (TMP)IBA
01/2018
1UracilIBA
01/2016
1Azathioprine (Imuran)FDA LinkGeneric
08/2013
1bis(3',5')-cyclic diguanylic acidIBA
08/2013
1Pharmaceutical PreparationsIBA
08/2013
1NitratesIBA
11/2012

Therapy/Procedure

1Ligation
01/2022
1Therapeutics
08/2012